MLchartDataset catalogue

Affinity

Term · Chemistry · MLC-T-CHM-000316

The strength of the non-covalent binding interaction between two molecules, such as a ligand and a receptor, or an antibody and an antigen. It is quantitatively expressed by the dissociation constant (Kd), which represents the concentration of ligand at which half of the binding sites are occupied. A lower Kd value indicates higher affinity.

Table 1. Record
IdentifierMLC-T-CHM-000316
FieldChemistry
SubjectAnalytical Chemistry
Synonymsbinding affinity
ReferencesPAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1135 (https://doi.org/10.1515/pac-2016-1120)
Record as JSON 
{
  "id": "MLC-T-CHM-000316",
  "term": "Affinity",
  "field": "Chemistry",
  "definition": "The strength of the non-covalent binding interaction between two molecules, such as a ligand and a receptor, or an antibody and an antigen. It is quantitatively expressed by the dissociation constant (Kd), which represents the concentration of ligand at which half of the binding sites are occupied. A lower Kd value indicates higher affinity.",
  "synonyms": [
    "binding affinity"
  ],
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1135 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/affinity/"
}

Record 336 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.