MLchartDataset catalogue

Bound/free ratio

Term · Chemistry · MLC-T-CHM-001454

The ratio of the concentration of a substance that is bound to a specific binding partner (such as a receptor or antibody) to the concentration of the same substance that remains unbound or free in solution. This ratio is a measure of binding affinity and the extent of interaction between a ligand and its binding site. It is commonly determined in equilibrium binding assays.

Table 1. Record
IdentifierMLC-T-CHM-001454
FieldChemistry
SubjectAnalytical Chemistry
ReferencesPAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1137 (https://doi.org/10.1515/pac-2016-1120)
Record as JSON
{
  "id": "MLC-T-CHM-001454",
  "term": "Bound/free ratio",
  "field": "Chemistry",
  "definition": "The ratio of the concentration of a substance that is bound to a specific binding partner (such as a receptor or antibody) to the concentration of the same substance that remains unbound or free in solution. This ratio is a measure of binding affinity and the extent of interaction between a ligand and its binding site. It is commonly determined in equilibrium binding assays.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1137 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/bound-free-ratio/"
}

Record 1,556 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.