Alternating least squares regression

{
  "id": "MLC-T-CHM-000456",
  "term": "Alternating least squares regression",
  "field": "Chemistry",
  "definition": "An iterative computational method for resolving multivariate data into a set of underlying contributions or factors. The algorithm alternates between fixing one set of parameters (for example, concentrations) and solving for the other (for example, spectra) using a least squares fit, repeating the process until the solution converges. This technique is widely applied in chemometrics for mixture analysis, such as determining the pure component spectra from a series of mixture spectra.",
  "synonyms": [
    "alternating regression"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "multivariate data"
  ],
  "references": [
    "PAC, 2016, 88, 407. 'Vocabulary of concepts and terms in chemometrics (IUPAC Recommendations 2016)' on page 417 (https://doi.org/10.1515/pac-2015-0605)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/alternating-least-squares-regression/"
}