Antihistamine

{
  "id": "MLC-T-CHM-000688",
  "term": "Antihistamine",
  "field": "Chemistry",
  "definition": "A drug that counteracts the effects of histamine, a substance released by the body during allergic reactions. These compounds act by blocking histamine from binding to its receptors on nerve endings, smooth muscle, and gland cells. First-generation antihistamines like diphenhydramine cross the blood-brain barrier and cause sedation, whereas second-generation agents like loratadine do not.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1168 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/antihistamine/"
}