Aryl hydrocarbon receptor

{
  "id": "MLC-T-CHM-000823",
  "term": "Aryl hydrocarbon receptor",
  "field": "Chemistry",
  "definition": "A ligand-activated transcription factor that mediates the toxic and biological effects of certain environmental contaminants, such as dioxins and polycyclic aromatic hydrocarbons. Upon binding its ligand, the receptor translocates to the nucleus and forms a complex with the aryl hydrocarbon receptor nuclear translocator (ARNT). This complex then binds to specific DNA sequences, known as dioxin response elements, to regulate gene expression.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "transcription factor"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 727 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/aryl-hydrocarbon-receptor/"
}