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Atmospheric pressure matrix-assisted laser desorption/ionization

Term · Chemistry · MLC-T-CHM-000885

An ionization method in mass spectrometry where a sample, embedded in a matrix, is desorbed and ionized by a laser pulse at atmospheric pressure. The matrix absorbs the laser energy, transferring it to the analyte molecules, which then become ionized. This technique is particularly effective for analyzing large, non-volatile biomolecules such as proteins and polymers.

Table 1. Record
IdentifierMLC-T-CHM-000885
FieldChemistry
SubjectAnalytical Chemistry
ReferencesPAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1523 (https://doi.org/10.1351/PAC-REC-06-04-06)
Record as JSON 
{
  "id": "MLC-T-CHM-000885",
  "term": "Atmospheric pressure matrix-assisted laser desorption/ionization",
  "field": "Chemistry",
  "definition": "An ionization method in mass spectrometry where a sample, embedded in a matrix, is desorbed and ionized by a laser pulse at atmospheric pressure. The matrix absorbs the laser energy, transferring it to the analyte molecules, which then become ionized. This technique is particularly effective for analyzing large, non-volatile biomolecules such as proteins and polymers.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1523 (https://doi.org/10.1351/PAC-REC-06-04-06)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/atmospheric-pressure-matrix-assisted-laser-desorption-ionization/"
}

Record 952 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.