Matrix-assisted laser desorption electrospray ionization mass spectrometry

{
  "id": "MLC-T-CHM-007032",
  "term": "Matrix-assisted laser desorption electrospray ionization mass spectrometry",
  "field": "Chemistry",
  "definition": "An atmospheric-pressure ionization method in which a pulsed laser desorbs neutral analyte molecules from a sample containing a matrix, such as water ice or a MALDI matrix, and the plume is intercepted by charged electrospray droplets that ionize it. The ions resemble those from electrospray, including multiple charging, and the method is used for imaging of tissue sections.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "desorption atmospheric pressure photoionization mass spectrometry",
    "desorption electrospray ionization mass spectrometry",
    "electrospray laser desorption ionization mass spectrometry",
    "extractive electrospray ionization mass spectrometry",
    "laser ablation electrospray ionization mass spectrometry"
  ],
  "references": [
    "PAC, 2020, 92, 1781. 'Glossary of methods and terms used in surface chemical analysis (IUPAC Recommendations 2020)' on page 1788 (https://doi.org/10.1515/pac-2019-0404)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/matrix-assisted-laser-desorption-electrospray-ionization-mass-spectrometry/"
}