Electrospray laser desorption ionization mass spectrometry

{
  "id": "MLC-T-CHM-013065",
  "term": "Electrospray laser desorption ionization mass spectrometry",
  "field": "Chemistry",
  "definition": "A two-step, ambient ionization technique for mass spectrometry where a pulsed laser desorbs neutral molecules from a sample surface, and a subsequent electrospray plume ionizes these gas-phase molecules. The laser ablation and ionization processes are spatially and temporally separated, allowing independent control over each step. This method is applied to the direct analysis of complex samples, including biological tissues, polymers, and dried liquid spots.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "desorption atmospheric pressure photoionization mass spectrometry",
    "desorption electrospray ionization mass spectrometry",
    "extractive electrospray ionization mass spectrometry"
  ],
  "references": [
    "PAC, 2020, 92, 1781. 'Glossary of methods and terms used in surface chemical analysis (IUPAC Recommendations 2020)' on page 1786 (https://doi.org/10.1515/pac-2019-0404)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/electrospray-laser-desorption-ionization-mass-spectrometry/"
}