Laser desorption ionization

{
  "id": "MLC-T-CHM-006458",
  "term": "Laser desorption ionization",
  "field": "Chemistry",
  "definition": "A process in which a pulsed laser hitting a solid or liquid sample produces gas-phase ions directly. Without a matrix it often fragments organic analytes considerably, which is why matrix-assisted laser desorption/ionization (MALDI) was developed for large or labile molecules. Direct laser desorption ionization works well for inorganic materials, metals and strongly absorbing small molecules such as polycyclic aromatic hydrocarbons.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1559 (https://doi.org/10.1351/PAC-REC-06-04-06)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/laser-desorption-ionization/"
}