Matrix-assisted laser desorption/ionization mass spectrometry

{
  "id": "MLC-T-CHM-007033",
  "term": "Matrix-assisted laser desorption/ionization mass spectrometry",
  "field": "Chemistry",
  "definition": "An ionization technique used in mass spectrometry where an analyte is co-crystallized with a large excess of a matrix compound. A laser pulse then irradiates the mixture, causing the matrix to absorb energy, vaporize, and transfer charge to the analyte, producing gas-phase ions. This method is widely used for analyzing large biomolecules such as proteins and polymers.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2020, 92, 1781. 'Glossary of methods and terms used in surface chemical analysis (IUPAC Recommendations 2020)' on page 1788 (https://doi.org/10.1515/pac-2019-0404)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/matrix-assisted-laser-desorption-ionization-mass-spectrometry/"
}