Coloboma

{
  "id": "MLC-T-CHM-002248",
  "term": "Coloboma",
  "field": "Chemistry",
  "definition": "A congenital condition characterized by a gap or defect in one of the ocular structures, resulting from incomplete closure of the embryonic optic fissure during fetal development. The malformation can affect the iris, creating a keyhole appearance, or other parts of the eye like the retina, choroid, or optic disc. Its presence can be an indicator of prenatal exposure to certain teratogenic substances.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "congenital",
    "retina"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 738 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/coloboma/"
}