Constitutive activity

{
  "id": "MLC-T-CHM-002473",
  "term": "Constitutive activity",
  "field": "Chemistry",
  "definition": "The intrinsic activity of a receptor in the absence of any ligand binding, indicating that the receptor can elicit a biological response without external stimulation. This activity arises from the receptor's natural conformation and its ability to interact with downstream signaling pathways. It is often measured as a baseline response in experimental systems.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1731 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/constitutive-activity/"
}