Intrinsic activity
Term · Chemistry · MLC-T-CHM-006024
The maximal effect a drug can produce once it has bound to its receptor, relative to the maximal effect of a full agonist. A full agonist has an intrinsic activity of 1, while a partial agonist has an intrinsic activity between 0 and 1. Antagonists have an intrinsic activity of 0, as they bind but produce no effect.
| Identifier | MLC-T-CHM-006024 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1247 (https://doi.org/10.1351/pac200779071153) |
Record as JSON
{
"id": "MLC-T-CHM-006024",
"term": "Intrinsic activity",
"field": "Chemistry",
"definition": "The maximal effect a drug can produce once it has bound to its receptor, relative to the maximal effect of a full agonist. A full agonist has an intrinsic activity of 1, while a partial agonist has an intrinsic activity between 0 and 1. Antagonists have an intrinsic activity of 0, as they bind but produce no effect.",
"subject": "Chemistry and Human Health",
"references": [
"PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1247 (https://doi.org/10.1351/pac200779071153)"
],
"url": "https://mlchart.com/terminology/chemistry/intrinsic-activity/"
}
Record 6,394 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.