Partial agonist

{
  "id": "MLC-T-CHM-008477",
  "term": "Partial agonist",
  "field": "Chemistry",
  "definition": "A ligand that binds to and activates a receptor but produces only a partial response compared to a full agonist, even at saturating concentrations. It possesses both affinity and intrinsic activity, but its maximal efficacy is less than that of a full agonist. These compounds can act as antagonists in the presence of a full agonist.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "efficacy"
  ],
  "references": [
    "PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1150 (https://doi.org/10.1351/PAC-REC-09-05-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/partial-agonist/"
}