Spare receptor

{
  "id": "MLC-T-CHM-011075",
  "term": "Spare receptor",
  "field": "Chemistry",
  "definition": "Receptors that exist in excess of the number required to elicit a maximal biological response when activated by an agonist. This phenomenon allows for a maximal effect even when only a fraction of the total receptors are occupied. The presence of spare receptors increases the sensitivity of a cell or tissue to an agonist.",
  "synonyms": [
    "receptor reserve"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1751 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/spare-receptor/"
}