Corona discharge ionization

{
  "id": "MLC-T-CHM-002589",
  "term": "Corona discharge ionization",
  "field": "Chemistry",
  "definition": "A soft ionization technique that uses a gas discharge at atmospheric pressure to create reactant ions from a solvent or reagent gas, which then ionize analyte molecules. A high electric potential is applied to a sharp electrode, creating a localized plasma, or corona, that generates ions through a series of gas-phase reactions. This method is a form of atmospheric pressure chemical ionization (APCI) and is commonly used as an ion source for liquid chromatography-mass spectrometry.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "corona discharge"
  ],
  "references": [
    "PAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1533 (https://doi.org/10.1351/PAC-REC-06-04-06)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/corona-discharge-ionization/"
}