Druggability

{
  "id": "MLC-T-CHM-003452",
  "term": "Druggability",
  "field": "Chemistry",
  "definition": "The likelihood that a given biological target can be modulated by a small molecule drug with acceptable potency and selectivity. This concept assesses the feasibility of developing a drug against a specific protein or pathway. Factors influencing druggability include the presence of binding pockets and the target's role in disease pathology.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1733 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/druggability/"
}