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Electrophilic substitution

Term · Chemistry · MLC-T-CHM-003780

A type of organic reaction where an electrophile replaces an atom or group, typically hydrogen, on an organic compound. This reaction is characteristic of aromatic compounds, where the aromatic ring acts as an electron source for the attacking electrophile. A classic example is the nitration of benzene.

Table 1. Record
IdentifierMLC-T-CHM-003780
FieldChemistry
SubjectOrganic and Biomolecular Chemistry
ReferencesPAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 412 (https://doi.org/10.1515/pac-2018-1010)
Record as JSON
{
  "id": "MLC-T-CHM-003780",
  "term": "Electrophilic substitution",
  "field": "Chemistry",
  "definition": "A type of organic reaction where an electrophile replaces an atom or group, typically hydrogen, on an organic compound. This reaction is characteristic of aromatic compounds, where the aromatic ring acts as an electron source for the attacking electrophile. A classic example is the nitration of benzene.",
  "subject": "Organic and Biomolecular Chemistry",
  "references": [
    "PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 412 (https://doi.org/10.1515/pac-2018-1010)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/electrophilic-substitution/"
}

Record 4,009 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.