Nucleophilic substitution
Term · Chemistry · MLC-T-CHM-008138
A type of reaction in which an electron-rich nucleophile replaces a leaving group on an electron-deficient electrophilic center. The nucleophile donates an electron pair to form a new bond, while the leaving group departs with its bonding electrons. This process is common in organic chemistry, particularly with alkyl halides and acyl compounds.
| Identifier | MLC-T-CHM-008138 |
|---|---|
| Field | Chemistry |
| Subject | Organic and Biomolecular Chemistry |
| References | PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 473 (https://doi.org/10.1515/pac-2018-1010) |
Record as JSON
{
"id": "MLC-T-CHM-008138",
"term": "Nucleophilic substitution",
"field": "Chemistry",
"definition": "A type of reaction in which an electron-rich nucleophile replaces a leaving group on an electron-deficient electrophilic center. The nucleophile donates an electron pair to form a new bond, while the leaving group departs with its bonding electrons. This process is common in organic chemistry, particularly with alkyl halides and acyl compounds.",
"subject": "Organic and Biomolecular Chemistry",
"references": [
"PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 473 (https://doi.org/10.1515/pac-2018-1010)"
],
"url": "https://mlchart.com/terminology/chemistry/nucleophilic-substitution/"
}
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