Globule-to-coil transition

{
  "id": "MLC-T-CHM-004913",
  "term": "Globule-to-coil transition",
  "field": "Chemistry",
  "definition": "A conformational change in a polymer chain from a compact, collapsed globule state to an expanded, random coil state. This transition typically occurs upon changes in solvent quality, temperature, or pH, which alter the balance between intramolecular and polymer-solvent interactions. It is the reverse process of the coil-to-globule transition.",
  "subject": "Polymer",
  "see_also": [
    "coil-to-globule transition"
  ],
  "references": [
    "PAC, 2012, 85, 463. 'Terminology for aggregation and self-assembly in polymer science (IUPAC Recommendations 2013)' on page 472 (https://doi.org/10.1351/PAC-REC-12-03-12)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/globule-to-coil-transition/"
}