Globule

Term · Chemistry · MLC-T-CHM-004912

A compact, roughly spherical or ovoid conformation of a single macromolecule, in which the constitutional units pack closely instead of forming an open coil. Globules form in dilute solution when the solvent is poor, because attraction between segments outweighs polymer-solvent contacts, and they also occur in folded globular proteins. The change between a globule and an expanded coil is called the coil-to-globule transition, or globule-to-coil in the reverse direction.

Table 1. Record
Identifier	MLC-T-CHM-004912
Field	Chemistry
Subject	Polymer
References	PAC, 2012, 85, 463. 'Terminology for aggregation and self-assembly in polymer science (IUPAC Recommendations 2013)' on page 472 (https://doi.org/10.1351/PAC-REC-12-03-12)

Record as JSON

{
  "id": "MLC-T-CHM-004912",
  "term": "Globule",
  "field": "Chemistry",
  "definition": "A compact, roughly spherical or ovoid conformation of a single macromolecule, in which the constitutional units pack closely instead of forming an open coil. Globules form in dilute solution when the solvent is poor, because attraction between segments outweighs polymer-solvent contacts, and they also occur in folded globular proteins. The change between a globule and an expanded coil is called the coil-to-globule transition, or globule-to-coil in the reverse direction.",
  "subject": "Polymer",
  "references": [
    "PAC, 2012, 85, 463. 'Terminology for aggregation and self-assembly in polymer science (IUPAC Recommendations 2013)' on page 472 (https://doi.org/10.1351/PAC-REC-12-03-12)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/globule/"
}

Record 5,201 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.