Graft-versus-host reaction

{
  "id": "MLC-T-CHM-004990",
  "term": "Graft-versus-host reaction",
  "field": "Chemistry",
  "definition": "An immune response initiated by immunocompetent cells present in a transplanted graft against the tissues of the recipient host. This reaction is mediated primarily by donor T lymphocytes that recognize host antigens as foreign. It is the underlying immunological process that can lead to graft-versus-host disease.",
  "synonyms": [
    "GVH reaction"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1171 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/graft-versus-host-reaction/"
}