MLchartDataset catalogue

Heterophile antibody

Term · Chemistry · MLC-T-CHM-005268

An antibody that reacts with antigens from unrelated species, or with antigens that are structurally similar but not identical to the original antigen that stimulated its production. These antibodies can sometimes cause false positive results in diagnostic tests due to their broad reactivity. A well-known example is the antibody produced in infectious mononucleosis that reacts with sheep red blood cells.

Table 1. Record
IdentifierMLC-T-CHM-005268
FieldChemistry
SubjectChemistry and Human Health
Synonymsheterophilic antibody
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1175 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoForssman antigen
Record as JSON
{
  "id": "MLC-T-CHM-005268",
  "term": "Heterophile antibody",
  "field": "Chemistry",
  "definition": "An antibody that reacts with antigens from unrelated species, or with antigens that are structurally similar but not identical to the original antigen that stimulated its production. These antibodies can sometimes cause false positive results in diagnostic tests due to their broad reactivity. A well-known example is the antibody produced in infectious mononucleosis that reacts with sheep red blood cells.",
  "synonyms": [
    "heterophilic antibody"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Forssman antigen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1175 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/heterophile-antibody/"
}

Record 5,581 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.