Cross reaction

{
  "id": "MLC-T-CHM-002708",
  "term": "Cross reaction",
  "field": "Chemistry",
  "definition": "An undesirable interaction where an analytical reagent or antibody designed to detect a specific analyte also reacts with other, structurally similar substances. This lack of specificity can lead to false positive results or inaccurate quantification in immunoassays and other binding assays. Careful assay design and validation are necessary to minimize cross reactions.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "competitive binding assay"
  ],
  "references": [
    "PAC, 1994, 66, 2513. 'Nomenclature for radioanalytical chemistry (IUPAC Recommendations 1994)' on page 2517 (https://doi.org/10.1351/pac199466122513)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cross-reaction/"
}