Non-specific binding

{
  "id": "MLC-T-CHM-008053",
  "term": "Non-specific binding",
  "field": "Chemistry",
  "definition": "The undesirable attachment of an analyte or reagent to surfaces or components of a system that are not the intended target. This binding does not involve specific molecular recognition events, such as antibody-antigen interactions or enzyme-substrate binding. It can lead to false positive signals or reduced assay sensitivity in bioanalytical methods.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "nucleotide sequence"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1185 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/non-specific-binding/"
}