Hold-up time

{
  "id": "MLC-T-CHM-005332",
  "term": "Hold-up time",
  "field": "Chemistry",
  "definition": "The time required for an unretained component to pass through a chromatographic column from the point of injection to the detector. This value represents the time taken by the mobile phase to traverse the column. It is a fundamental parameter in chromatography, often denoted as tM or t0, and is used to calculate retention factors.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 196 (https://doi.org/10.1515/pac-2017-0111)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/hold-up-time/"
}