Retention volume of an unretained compound

{
  "id": "MLC-T-CHM-010294",
  "term": "Retention volume of an unretained compound",
  "field": "Chemistry",
  "definition": "The volume of mobile phase required to elute a compound that does not interact with the stationary phase from a chromatographic column. This volume, also known as the mobile phase holdup volume or dead volume, represents the interstitial volume of the column. It is used to calculate adjusted retention volumes and retention factors.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "retention volume",
    "retention time of an unretained compound"
  ],
  "references": [
    "PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 212 (https://doi.org/10.1515/pac-2017-0111)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/retention-volume-of-an-unretained-compound/"
}