Itai-itai disease

{
  "id": "MLC-T-CHM-006271",
  "term": "Itai-itai disease",
  "field": "Chemistry",
  "definition": "A chronic and painful bone disease caused by severe cadmium poisoning, characterized by osteomalacia, kidney dysfunction, and bone fractures. The name, meaning 'ouch-ouch' in Japanese, reflects the intense pain experienced by affected individuals. This condition was first identified in Japan due to industrial pollution of rivers with cadmium, leading to contamination of the food chain.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1248 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/itai-itai-disease/"
}