Large granular lymphocyte

{
  "id": "MLC-T-CHM-006443",
  "term": "Large granular lymphocyte",
  "field": "Chemistry",
  "definition": "A type of lymphocyte characterized by its large size and the presence of prominent cytoplasmic granules. These cells constitute a morphologically defined population that includes both natural killer (NK) cells and a subset of cytotoxic T lymphocytes. They are identified in blood smears by their distinct appearance, featuring an abundant cytoplasm and azurophilic granules.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "CD8",
    "lymphocyte",
    "cytotoxic T lymphocyte",
    "killer cell",
    "natural killer cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1200 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/large-granular-lymphocyte/"
}