Linked recognition

{
  "id": "MLC-T-CHM-006649",
  "term": "Linked recognition",
  "field": "Chemistry",
  "definition": "The cellular interaction mechanism required for the activation of a B lymphocyte by a thymus-dependent antigen. It involves a helper T lymphocyte recognizing a processed peptide from the antigen presented by the B cell, while the B cell's surface immunoglobulin recognizes a separate epitope on the intact antigen. This dual recognition provides the B cell with the necessary signals to proliferate and differentiate into an antibody-producing plasma cell.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "helper T lymphocyte",
    "thymus-dependent antigen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1202 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/linked-recognition/"
}