T-cell-dependent antibody response

{
  "id": "MLC-T-CHM-011837",
  "term": "T-cell-dependent antibody response",
  "field": "Chemistry",
  "definition": "An immune pathway for antibody production that requires the direct interaction and collaboration between B lymphocytes and helper T lymphocytes. B cells present a processed antigen to a specific helper T cell, which in turn provides signals that stimulate the B cell to proliferate, differentiate into plasma cells, and produce high-affinity antibodies. This response generates long-lived memory B cells and is characteristic of the immune reaction to protein antigens.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "immunotoxic",
    "T-dependent antigen",
    "sheep red blood cell antigen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1249 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/t-cell-dependent-antibody-response/"
}