Thymus-dependent antigen

{
  "id": "MLC-T-CHM-012046",
  "term": "Thymus-dependent antigen",
  "field": "Chemistry",
  "definition": "An antigen that requires the assistance of helper T lymphocytes to stimulate B lymphocytes into producing antibodies. The B cell processes the antigen and presents it to a specific helper T cell, which in turn provides signals that activate the B cell to proliferate and differentiate into plasma cells. Most protein antigens are thymus-dependent, leading to the generation of memory B cells.",
  "synonyms": [
    "TD antigen"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "T lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1253 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/thymus-dependent-antigen/"
}