Thymus-independent antigen

{
  "id": "MLC-T-CHM-012047",
  "term": "Thymus-independent antigen",
  "field": "Chemistry",
  "definition": "An antigen capable of directly stimulating B lymphocytes to produce antibodies without the involvement of T lymphocytes. These antigens possess repetitive structural motifs, such as those found on bacterial polysaccharides or lipopolysaccharides, that can cross-link B cell receptors. The resulting immune response primarily produces IgM antibodies and does not generate long-lasting immunological memory.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "T lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1253 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/thymus-independent-antigen/"
}