Macropinocytosis

{
  "id": "MLC-T-CHM-006888",
  "term": "Macropinocytosis",
  "field": "Chemistry",
  "definition": "A clathrin-independent endocytic pathway characterized by the formation of large, irregular membrane protrusions that engulf extracellular fluid and its contents. This process is distinct from receptor-mediated endocytosis and is often triggered by growth factors or other signaling molecules. Macropinocytosis is particularly active in antigen-presenting cells like dendritic cells, facilitating the uptake of antigens.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "dendritic cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1208 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/macropinocytosis/"
}