MLchartDataset catalogue

Maximum additive concentration

Term · Chemistry · MLC-T-CHM-007043

The largest concentration of a poorly soluble substance, usually a drug, that a given surfactant solution can take up by micellar solubilization while remaining a clear solution. Above this value the mixture turns turbid or the excess separates out. The value rises with surfactant concentration beyond the point where micelles first form, because more micelles are present to hold the solubilized substance.

Table 1. Record
IdentifierMLC-T-CHM-007043
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 990 (https://doi.org/10.1351/PAC-REC-04-10-14)
Record as JSON
{
  "id": "MLC-T-CHM-007043",
  "term": "Maximum additive concentration",
  "field": "Chemistry",
  "definition": "The largest concentration of a poorly soluble substance, usually a drug, that a given surfactant solution can take up by micellar solubilization while remaining a clear solution. Above this value the mixture turns turbid or the excess separates out. The value rises with surfactant concentration beyond the point where micelles first form, because more micelles are present to hold the solubilized substance.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 990 (https://doi.org/10.1351/PAC-REC-04-10-14)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/maximum-additive-concentration/"
}

Record 7,464 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.