Menarche

{
  "id": "MLC-T-CHM-007173",
  "term": "Menarche",
  "field": "Chemistry",
  "definition": "The first menstrual bleeding in a female, which signals the beginning of her reproductive lifespan. This event indicates the maturation of the hypothalamic-pituitary-ovarian axis, initiating the hormonal cycles that regulate ovulation and menstruation. The age of onset is influenced by genetic, nutritional, and environmental factors, with the global average being approximately 12 to 13 years.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "menstrual cycle"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 776 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/menarche/"
}