Methemoglobin-forming substance

{
  "id": "MLC-T-CHM-007276",
  "term": "Methemoglobin-forming substance",
  "field": "Chemistry",
  "definition": "A chemical compound that, upon exposure or metabolism, induces the oxidation of the ferrous iron in hemoglobin to its ferric state, forming methemoglobin. Examples include nitrites, aniline derivatives, and certain drugs. Exposure to these substances can lead to methemoglobinemia, impairing oxygen transport in the blood.",
  "synonyms": [
    "methaemoglobin-forming substance"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1260 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/methemoglobin-forming-substance/"
}