Methemoglobinaemia

{
  "id": "MLC-T-CHM-007275",
  "term": "Methemoglobinaemia",
  "field": "Chemistry",
  "definition": "A condition characterized by the presence of an abnormally high concentration of methemoglobin in the blood. Methemoglobin is a form of hemoglobin in which the iron in the heme group is oxidized from the ferrous (Fe2+) to the ferric (Fe3+) state, rendering it incapable of binding oxygen. This leads to reduced oxygen delivery to tissues, causing cyanosis and hypoxia.",
  "synonyms": [
    "methaemoglobinaemia"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1260 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/methemoglobinaemia/"
}