Micronucleus test

{
  "id": "MLC-T-CHM-007343",
  "term": "Micronucleus test",
  "field": "Chemistry",
  "definition": "A cytogenetic assay used to detect chromosomal damage or aneuploidy in cells by identifying micronuclei. Micronuclei are small, extra nuclear bodies that contain lagging chromosomes or acentric chromosome fragments that were not incorporated into the main nucleus during cell division. This test is widely used in genotoxicity assessment to identify clastogens (agents causing chromosome breakage) and aneugens (agents causing chromosome loss).",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "aneugen",
    "clastogen"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 779 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/micronucleus-test/"
}