Non-ideal, linear chromatography

{
  "id": "MLC-T-CHM-008026",
  "term": "Non-ideal, linear chromatography",
  "field": "Chemistry",
  "definition": "A chromatographic process characterized by a linear distribution isotherm, meaning the partition coefficient is constant, but where other factors cause deviations from ideal behavior. These non-ideal effects include axial dispersion, slow mass transfer kinetics, and finite column efficiency. Such conditions lead to peak broadening and reduced resolution despite a linear relationship between solute concentration in the stationary and mobile phases.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "chromatography",
    "linear distribution isotherm"
  ],
  "references": [
    "PAC, 1996, 68, 1591. 'Nomenclature for non-linear chromatography (IUPAC Recommendations 1996)' on page 1594 (https://doi.org/10.1351/pac199668081591)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/non-ideal-linear-chromatography/"
}