Non-linear distribution isotherm

{
  "id": "MLC-T-CHM-008034",
  "term": "Non-linear distribution isotherm",
  "field": "Chemistry",
  "definition": "A relationship describing the equilibrium partitioning of a solute between the stationary and mobile phases in chromatography, where the concentration in one phase is not directly proportional to the concentration in the other. This non-proportionality means the partition coefficient changes with solute concentration. It is a characteristic feature of non-linear chromatography, leading to asymmetric peak shapes.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "chromatography",
    "distribution isotherm"
  ],
  "references": [
    "PAC, 1996, 68, 1591. 'Nomenclature for non-linear chromatography (IUPAC Recommendations 1996)' on page 1593 (https://doi.org/10.1351/pac199668081591)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/non-linear-distribution-isotherm/"
}