PC-12 cell

{
  "id": "MLC-T-CHM-008557",
  "term": "PC-12 cell",
  "field": "Chemistry",
  "definition": "A cell line derived from a rat pheochromocytoma, a tumor of the adrenal medulla. These cells exhibit characteristics of neuroendocrine cells and can differentiate into sympathetic neuron-like cells in the presence of nerve growth factor. They are widely used as an in vitro model for studying neuronal differentiation, neurotoxicity, and neurosecretion.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "nerve growth factor",
    "pheochromocytoma"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 896 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pc-12-cell/"
}