Phorbol 12-myristate 13-acetate

{
  "id": "MLC-T-CHM-008770",
  "term": "Phorbol 12-myristate 13-acetate",
  "field": "Chemistry",
  "definition": "A potent tumor promoter and a synthetic analog of diacylglycerol, which is a natural activator of protein kinase C (PKC). This compound is widely used in research to activate PKC and study its downstream signaling pathways. It can induce cell proliferation, differentiation, and apoptosis depending on the cell type.",
  "synonyms": [
    "tetradecanoyl phorbol acetate (TPA)"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "mitogen",
    "protein kinase C"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1228 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/phorbol-12-myristate-13-acetate/"
}