Allostery

{
  "id": "MLC-T-CHM-000435",
  "term": "Allostery",
  "field": "Chemistry",
  "definition": "The regulation of a protein's activity or binding affinity at one site by the binding of an effector molecule at a different, distinct site. This mechanism involves conformational changes in the protein structure that are transmitted from the allosteric site to the active or orthosteric site. It is a fundamental regulatory principle in biochemistry.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "binding site",
    "conformation",
    "effector",
    "enzymes"
  ],
  "references": [
    "PAC, 1994, 66, 2587. 'Glossary of bioanalytical nomenclature - Part 1: General terminology, body fluids, enzymology, immunology (IUPAC Recommendations 1994)' on page 2593 (https://doi.org/10.1351/pac199466122587)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/allostery/"
}