Allosteric enzymes

{
  "id": "MLC-T-CHM-000434",
  "term": "Allosteric enzymes",
  "field": "Chemistry",
  "definition": "Enzymes that possess a regulatory site, known as the allosteric site, which is distinct from their catalytic active site. The binding of a specific molecule, an allosteric effector, to this site induces a conformational change in the enzyme that modifies its activity. This regulation can be either positive (activation) or negative (inhibition) and is a key feature of metabolic pathway feedback control, differing from competitive inhibition which occurs at the active site.",
  "subject": "Chemistry and the Environment",
  "see_also": [
    "enzymes",
    "activator",
    "effector",
    "inhibitor",
    "substrate"
  ],
  "references": [
    "PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 146 (https://doi.org/10.1351/pac199264010143)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/allosteric-enzymes/"
}