Competitive inhibition

{
  "id": "MLC-T-CHM-002310",
  "term": "Competitive inhibition",
  "field": "Chemistry",
  "definition": "A type of enzyme inhibition where an inhibitor molecule binds reversibly to the active site of an enzyme, preventing the substrate from binding. The inhibitor and substrate compete for the same binding site, and increasing substrate concentration can overcome the inhibition. This inhibition increases the apparent Michaelis constant (Km) but does not change the maximum reaction rate (Vmax).",
  "subject": "Physical and Biophysical Chemistry",
  "see_also": [
    "adsorption",
    "catalyst"
  ],
  "references": [
    "PAC, 1976, 46, 71. 'Manual of Symbols and Terminology for Physicochemical Quantities and Units - Appendix II. Definitions, Terminology and Symbols in Colloid and Surface Chemistry. Part II: Heterogeneous Catalysis' on page 83 (https://doi.org/10.1351/pac197646010071)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/competitive-inhibition/"
}