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Dual binding site

Term · Chemistry · MLC-T-CHM-003465

A characteristic of a biological macromolecule, such as an enzyme or receptor, that possesses two distinct regions capable of interacting with a ligand. These sites may bind the same or different molecules, leading to complex regulatory mechanisms or allosteric effects. Acetylcholinesterase, for example, has both an active site and a peripheral anionic site.

Table 1. Record
IdentifierMLC-T-CHM-003465
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1733 (https://doi.org/10.1351/PAC-REC-12-11-23)
See alsoMolecular target
Record as JSON
{
  "id": "MLC-T-CHM-003465",
  "term": "Dual binding site",
  "field": "Chemistry",
  "definition": "A characteristic of a biological macromolecule, such as an enzyme or receptor, that possesses two distinct regions capable of interacting with a ligand. These sites may bind the same or different molecules, leading to complex regulatory mechanisms or allosteric effects. Acetylcholinesterase, for example, has both an active site and a peripheral anionic site.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "molecular target"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1733 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/dual-binding-site/"
}

Record 3,681 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.