MLchartDataset catalogue

Alpha-synuclein

Term · Chemistry · MLC-T-CHM-000449

A small, soluble protein found abundantly in the brain, particularly in presynaptic terminals. Its precise physiological function is not fully understood, but it is implicated in synaptic plasticity and neurotransmitter release. Aggregation of alpha-synuclein into insoluble fibrils forms Lewy bodies, a hallmark of Parkinson's disease and other synucleinopathies.

Table 1. Record
IdentifierMLC-T-CHM-000449
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 845 (https://doi.org/10.1515/pac-2015-0103)
Record as JSON
{
  "id": "MLC-T-CHM-000449",
  "term": "Alpha-synuclein",
  "field": "Chemistry",
  "definition": "A small, soluble protein found abundantly in the brain, particularly in presynaptic terminals. Its precise physiological function is not fully understood, but it is implicated in synaptic plasticity and neurotransmitter release. Aggregation of alpha-synuclein into insoluble fibrils forms Lewy bodies, a hallmark of Parkinson's disease and other synucleinopathies.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 845 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/alpha-synuclein/"
}

Record 475 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.