Tau protein

{
  "id": "MLC-T-CHM-011827",
  "term": "Tau protein",
  "field": "Chemistry",
  "definition": "A microtubule-associated protein primarily found in neurons, where it stabilizes microtubules and regulates axonal transport. Hyperphosphorylation of this protein leads to its aggregation into neurofibrillary tangles, a hallmark pathology of Alzheimer's disease and other tauopathies. The degree of tau phosphorylation and aggregation correlates with disease progression.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Alzheimer disease",
    "astrocyte",
    "dementia",
    "oligodendrocyte"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 910 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/tau-protein/"
}