Autoimmune bullous skin disease
Term · Chemistry · MLC-T-CHM-000971
A group of chronic inflammatory skin disorders characterized by the formation of blisters (bullae) on the skin and mucous membranes. These conditions arise from an autoimmune response where the body produces autoantibodies that target specific proteins involved in cell adhesion within the skin. The disruption of these adhesion proteins leads to the separation of skin layers and subsequent blister formation, as seen in pemphigus and pemphigoid.
| Identifier | MLC-T-CHM-000971 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1137 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | Autoantibody; Autoimmune disease |
Record as JSON
{
"id": "MLC-T-CHM-000971",
"term": "Autoimmune bullous skin disease",
"field": "Chemistry",
"definition": "A group of chronic inflammatory skin disorders characterized by the formation of blisters (bullae) on the skin and mucous membranes. These conditions arise from an autoimmune response where the body produces autoantibodies that target specific proteins involved in cell adhesion within the skin. The disruption of these adhesion proteins leads to the separation of skin layers and subsequent blister formation, as seen in pemphigus and pemphigoid.",
"subject": "Chemistry and Human Health",
"see_also": [
"autoantibody",
"autoimmune disease"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1137 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/autoimmune-bullous-skin-disease/"
}
Record 1,045 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.